The SARSVID 2 virus that causes Covid-19
It has been almost a year
and a half since the global epidemic of covid-19 spread around the world,
during which time the cause of the epidemic and the virus called SARS-COV-2
have been scientifically studied. But there have been many
authoritative, strong, and shocking revelations, as well as many unconventional,
vague and unsubstantiated conspiracy theories about the virus and the epidemic of
covid-19 that have found their place
in our minds. Declared the result of an intentional or unintentional scientific
accident or denied it altogether, but over time these ambiguous ideas continued
to die their own deaths.
In recent times, these
ideas have been replaced by new conspiracy theories. At the top of the list is
the vaccine against SARS covidia 2, which is actually a way to control the
population. But in the end, even the earliest acceptance of this theory has
waned over time in the face of scientific research and the facts that emerge
from it.
As a result of ongoing
scientific research, it can now be said that it is a fact that the SARS-2
virus
has evolved as a result of natural evolution. Therefore, this virus
also has the same evolutionary principles that have been proven in other
organisms and viruses. Over the past year and a half, millions of samples of
the SARSVID
virus has been collected from
around the world, and genetic analysis of the virus derived from these
samples have been carried out in laboratories around the world. In other words,
GISAID is actually a search engine similar to Google for the genetic make-up of
SARSQUID
2 and the changes that take place in it. A comparative study of the genetic
material of millions of SARSQUID 2 makes it clear that The SARS-2
virus
is also undergoing genetic mutations, or in other words, an evolutionary
process.
The same evolutionary
process has led to the identification of more than two and a half thousand
species of SARSVID 2 virus, all of which are genetically very different
from each other. In scientific terms, these types are called Strain or Variant.
Now some important questions arise here. The first is why variants of this virus
are emerging. Second, what will be the benefit of making a variant of the virus?
Third, what will be the effect of this variant on the epidemic of covid-19? Fourth, will the vaccine
against SARSV2 be effective against this variant? The answer to all
these questions lies in understanding the evolutionary process of living
things. So before we move on to the answers to these questions, let's get
acquainted with biological evolution.
There are more than 25
million species of living things on the planet. These species, found in the
Earth's history of about five billion years is only one percent, and the
remaining 99 percent are extinct. According to the theory of biological
evolution, the current form of which every British living researcher, Charles
Robert Darwin, and many later scientists, reproduces more than necessary.
During this reproduction, he replicates the genetic material that he passed on
to the next generation. can go. This process of copying is not entirely secure,
but mistakes are made during the process, such as genetic mutations. These
mutations usually do no good to the organism, nor do they cause any harm, as
these mutations are passed on from generation to generation. They continue to
grow and grow to some extent.
This process is called
neutral selection. However, there are some mutations that result in organisms losing
or becoming less compatible with their environment. As a result, such organisms
gradually become extinct. This process is called negative selection. Rarely do
some genetic mutations occur, resulting in a new generation of organisms
becoming more adapted to their environment or to the same species. They are
better than other animals in one way or another, due to which they are able to
get more facilities than other animals of their own species in the environment.
For example, children of
the same parent can usually reach the end of their life with a single memory
leopard. These are leopards that are either older or smarter than their
siblings, or faster or faster. They can make long jumps, which gives them more
opportunities to breed and get food than their siblings, and they can continue
their breeding. This process is called positive selection, when the leopards,
which are relatively similar in size to their parents but remain weaker than
their siblings, are generally unable to reproduce. Therefore, they fall prey to
negative selection. Now, keeping in view the same evolutionary process, we find
the answers to the above four questions.
SARSwood 2
Because SARSVID
2 is a virus, like other viruses, it reproduces in other
organisms. This is a living human being in the case of SARSwood 2.
The SARSVID 2 virus attaches
to humans a protein called ACE2 in human cells through its Spike protein. After
attachment, some human proteins such as TBRRSS2 and Furin enter the virus
into human cells where the virus releases its genetic material. These genetic materials, like hijackers entering a plane, take control of the
plane. Takes control of the factors that occur in the cell, as a result of
which human cells begin to make genetic material and proteins instead of doing
their job. This process of copying the genetic material of the virus
polymerase a protein but this process is full of errors. Many of these errors
are corrected but some errors remain which are called mutilation in scientific
terms.
During the one and a half
year epidemic of covid-19, the SARS
Covid 2 virus has multiplied in more than 150 million humans. During
this time, it has replicated its genetic material in each human being, and
during this time many mutations have taken place. Surveys have identified more
than 2,500 species of SARSwood.
Genetic mutations are
neither beneficial nor harmful and some mutations are harmful and very specific
mutations are beneficial to the organism. Called Neutral Selection, Negative
Selection, and Positive Selection, respectively, the first of the more than two
and a half thousand species of SARSwidth are almost extinct by
either neutral or negative selection.
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SARS-2 viruses
However, changes in some
species of SARS covid 2 have given it some additional features, as a
result of which it can either retain its shape longer in the environment or
spread rapidly to humans or cause more severe disease in humans. Or can escape
the human immune system. Based on the characteristics of the SARS-2
viruses
that have such mutations. They are spreading faster in humans than other SARS-2
viruses.
In short, these variants
of SARS
Covid 2 has undergone a positive selection process. So far no new species have
been discovered which are basically divided into two groups called Variants of
concern and variants under investigation. The British type (B1.1.7) of the SARSV2
virus in South Africa, type
(B.1.351). The Brazilian variety (P.1) and the California variety (B.1.427 /
B.1.429) are counted among the variants of Vincent. Of these, the British type SARS
covid 2 spreads 50% faster than the Chinese variety, while other types have
the ability to evade antibodies caused by chronic infections or vaccines in the
immune system. Due to these features, these species of SARSVID 2 are becoming
more invasive in humans and are rapidly advancing their lineage to eradicate
other less harmful strains of the same virus.
The first variant of
concern to be discovered in the UK was the British version of SARSVID
2, which led to a rapid increase in viral infections in the UK and a third wave of SARSVID 2 infections or epidemics in Pakistan in recent days.
Dar is also being declared as such. The type CB.1.527 / B.1.529 discovered in
New York and the type (B1.617) or double variant found in India in recent times
are considered variants under investigations, according to the investigation so
far. However, it cannot be said that the epidemic is spreading rapidly due to
these variants or are spreading rapidly due to environmental factors and
negligence in SOPs.
The question now is
whether the existing vaccines against SARSVID 2 are effective against
these species. So far, more than ten vaccines against SARSVID 2 are being used
in humans. These vaccines are either mRNA or adenovirus or SARSVID
2. Or made from its ingredients. All of these vaccines are said to make
antibodies against the Spike protein of the SARS Covid 2 virus
once they enter the human body.
Therefore, when a person
is infected with the SARS covidia 2 virus, as if already
vaccinated, these antibodies attach to the spikes of the invading virus
protein and do not attach to the ACE2 protein of such human cells, which The virus
does not invade human cells, and genetic mutations have occurred in the
British, South African, Brazilian, and California varieties of the SARS-2
variants that result from the process, resulting in their Spike protein.
Significant changes have taken place in the structure, causing vaccine-derived
antibodies to weakly associate these types of SARS-2 with spike
proteins. As a result, if the vaccinated person is attacked by the early SARS-2
type The vaccine may be fully effective and the virus may not be able to
cause disease in such a person. However, if a vaccinated person is attacked by
new strains of SARS-2, the vaccine will provide protection against the virus,
but protection This intensity will be slightly lower.
In this situation, it is
important to ensure that the dose of existing vaccines is obtained first, so
that complete protection from the old and new strains of Sarzcovid 2 can be
provided. , So that new types of viruses do not invade. Research
institutes around the world have begun developing and analyzing vaccines
against new strains of the virus. Therefore, whenever these
vaccines are available, their dose should also be taken.
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